2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Dopamine Receptor
  5. Dopamine Receptor Activator

Dopamine Receptor Activator

Dopamine Receptor Isoform Comparison

Dopamine Receptor Activators (12):

Cat. No. Product Name Effect Purity
  • HY-P1764
    Secretoneurin, rat
    		Activator 99.59%
    Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII). Secretoneurin, rat induces dopamine release in the rat striatum in vivo and in vitro, and it exerts a very strong chemotactic effect on monocytes and eosinophils but not on granulocytes.
  • HY-N1745
    2'-O-Methylisoliquiritigenin
    		Activator 98.44%
    2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway.
  • HY-B1233A
    Octodrine hydrochloride
    		Activator ≥98.0%
    Octodrine (2-Amino-6-methylheptane) is a central nervous activator that increases the uptake of dopamine and noradrenaline. Octodrine is found to increase the pain threshold, cardiac rate (positive chronotropic effect) and myocardial contractility (positive inotropic effect).
  • HY-137447
    Pirepemat
    		Activator
    Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease. IRL752 is a selective enhancer of cortical dopamine, acetylcholine and norepinephrine.
  • HY-P1146A
    Semax acetate
    		Activator 99.91%
    Semax acetate is a nootropic neuroprotective peptide. Semax acetate can be used in the research of brain stroke.
  • HY-B1233
    Octodrine
    		Activator ≥98.0%
    Octodrine (2-Amino-6-methylheptane) is a central nervous stimulant that increases the uptake of dopamine and noradrenaline. Octodrine is found to increase the pain threshold, cardiac rate (positive chronotropic effect) and myocardial contractility (positive inotropic effect).
  • HY-108455
    N-Palmitoyl dopamine
    		Activator
    N-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide.
  • HY-121152
    Chiisanoside
    		Activator
    Chiisanoside exhibits neuroprotective, anticancer, antidepressant, anti-inflammatory, anti-obesity and anti-platelet activities. Chiisanoside inhibits tumor growth in H22 xenograft mouse model, through immunoregulation, induction of apoptosis and inhibition of angiogenesis. Chiisanoside attenuates Parkinson’s disease through regulation of Parkin/ZNF746/PGC-1α axis, and promotion of mitochondrial biogenesis.
  • HY-B0451AS6
    Dopamine-13C,15N hydrochloride
    		Activator
    Dopamine-13C,15N (hydrochloride) is the 13C and 15N labeled Dopamine hydrochloride[1].
  • HY-155466
    Boc-MIF-1-Am
    		Activator
    Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and is a bioconjugate of melanostatin (MIF-1) and amantadine. Boc-MIF-1-Am (200 μM) exhibited mild neurotoxicity in SH-SY5Y cells.
  • HY-123398
    RS-51324
    		Activator
    RS-51324 is an oral active antidepressant agent. RS-51324 inhibitts norepinephrine uptake and reverses of Reserpine (HY-N0480)-induced hypothermia.
  • HY-12244
    BB-22
    		Activator
    BB-22 is a cannabinoid wih dopamine (DA) stimulant properties. BB-22 shows affinity to CB1 receptors with a Ki value of 0.11 nM and an EC50 value of 2.9 nM.